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Home » Depression
Self-Medicating Increases Risk of Substance Abuse Problems
  • Anxiety
  • Depression
Feb26

Self-Medicating Increases Risk of Substance Abuse ...

posted by ATS

People who self-medicate — that is, to use alcohol or drugs to reduce unwanted feelings or anxiety — are at greater risk for a later substance abuse problem, according to a new study. Self-medicating also appears to up the risk for social phobia in people with anxiety. People typically self-medicate in an effort to avoid more formal treatment, whether it be with psychotherapy or medications. Canadian researchers led by Jennifer Robinson examined data collected through the National Institute on Alcohol Abuse and Alcoholism survey. Their study was designed to measure the occurrence of substance use disorders in individuals with anxiety...

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Possible Therapeutic Target For Depression And Addiction
  • Depression
Dec16

Possible Therapeutic Target For Depression And Add...

posted by ATS

Researchers studying mice are getting closer to understanding how stress affects mood and motivation for drugs. According to the researchers, blocking the stress cascade in brain cells may help reduce the effects of stress, which can include anxiety, depression and the pursuit of addictive drugs. A research team from St. Louis and Seattle reports in the Aug. 11 issue of the journal Neuron that in mice exposed to stress, a protein called p38α mitogen-activated protein kinase (MAPK) influences the animal’s behavior, contributing to depression-like symptoms and risk for addiction. The first author is Michael R. Bruchas, PhD, assistant...

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Neurological protein may hold the key to new treatments for depression
  • Depression
Nov22

Neurological protein may hold the key to new treat...

posted by ATS

Neuroscientists at the Centre for Addiction and Mental Health (CAMH) have developed a protein peptide that may be a novel type of highly targeted treatment for depression with a low side-effect profile. Depression affects one in ten Canadians at some time in their lives and is a leading cause of disability worldwide. The study published in this month’s Nature Medicine found that coupling between two dopamine receptors was significantly elevated in the brains of people who had been diagnosed with major depression. “We identified a potential therapeutic target for development of novel anti-depressants.” said Dr. Fang Liu,...

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Patients who use anti-depressants are more likely to suffer relapses of major depression
  • Depression
  • Major depressive disorder
Nov14

Patients who use anti-depressants are more likely ...

posted by ATS

Patients who use anti-depressants are much more likely to suffer relapses of major depression than those who use no medication at all, concludes a McMaster researcher.  In a paper that is likely to ignite new controversy in the hotly debated field of depression and medication, evolutionary psychologist Paul Andrews concludes that patients who have used anti-depressant medications can be nearly twice as susceptible to future episodes of major depression. Andrews, an assistant professor in the Department of Psychology, Neuroscience & Behaviour, is the lead author of a new paper in the journal Frontiers of Psychology. The meta-analysis...

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Depression: A Combination of Environmental, Psychological and Genetic Factors
  • Depression
Nov04

Depression: A Combination of Environmental, Psycho...

posted by ATS

Problems like anxiety and depression are caused by psychological and environmental factors, and are known to be influenced by genetic proclivities. However, it is still not clear how each factor affects the brain’s functions to induce anxious and depressive symptoms. To shed light on these interactions, a team from the Centre Émotion-Remédiation et Réalité Virtuelle (Center for Emotion Remediation and Virtual Reality, CNRS / UPMC / CHU Pitié Salpêtrière) has investigated the amygdala, a part of the brain that is hyperactive in individuals suffering from anxiety and depression.   The researchers have shown that its activity...

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Light Therapy
  • Depression
Aug31

Light Therapy

posted by ATS

Since the 1980's bright light has been used as an effective therapy for depressive and circadian rhythm disorders.

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Global Depression Statistics
  • Depression
Aug08

Global Depression St...

posted by ATS

Depression affects 121 million people worldwide. In can affect a person’s ability to work, form relationships, and destroy their quality of life. At its most severe depression can lead to suicide and is responsible for 850,000 deaths every year. New research published in BioMed...

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Study reveals new target for antidepressants
  • Depression
  • Mental disorder
  • Mental health
  • The Brain And Addiction
Apr12

Study reveals new ta...

posted by ATS

Study reveals new target for antidepressants By Kate Kelland   LONDON (Reuters) – British scientists using human stem cells say they have found out how antidepressants make new brain cells — a finding that should help drug researchers develop better and more efficient...

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